VRNxT is a sample preparation instrument that automates the volume reduction steps in your rare cell analysis workflow. With VRNxT you can add precision and accuracy to your workflow to minimize losses of precious cells and increase the throughput.
The instrument processes up to four samples in less than a minute and can be used for both live and fixed cells applications.
The instrument has two volume reduction programs for general purposes and two volume reduction programs dedicated to the DEPArray workflow.
Once a program is launched, the instrument uses the centrifugal force to collect and trap the excess liquid in the dedicated cap. Your rare cells of interest can be safely collected from the tube or directly processed for downstream molecular analysis.
Advantages of using VRNxT
Manual volume reduction it's time consuming and requires experience and manual skills for repeated pipetting with accuracy. This leads to user-dependent, variable results and increases the risk of losing precious cell(s).
The use of VRNxT has the following advantages:
No specific skillsets or training are required for operation, thereby delivering user-independent results with high reproducibility and success, with 99% of single cells retained after volume reduction.
Application in the DEPArray workflow for cells isolation and molecular analysis
In the DEPArray workflow VRNxT is the only volume reduction method that allows ultra-high precision supernatant removal during washing steps of the DEPArray workflow.
It automates the following processes:
Upstream of the DEPArray systems, the VRNxT precisely reduces the volume of input samples to approximately 12.5 μl in about 25 seconds, preparing them for loading into the DEPArray cartridge. Downstream of the DEPArray system, the device reduces sample volume in about eight seconds, making these samples ready for whole genome amplification with the Ampli1 WGA kit.
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