Data Analysis solution for MSB workflows
MSBiosuite is a cloud-based platform accessible through a web-based interface for the automated analysis of data generated by the sequencing of libraries obtained with Ampli1™ LowPass Kit, Ampli1™ OncoSeek Panel and DEPArray™ OncoSeek Panel.
MSBiosuite manages your entire workflow from uploading of raw data, data processing, to the downloading of results directly onto your computer and does not require any bioinformatic skill.
Available Data Analysis Pipelines
Ampli1™ LowPass Pipeline
The tailored analysis pipeline automates analysis of raw data obtained from the sequencing of DNA libraries produced with Ampli1 LowPass kits (for Illumina and Ion Torrent) and allows simultaneous analysis of multiple single-cell data and generation of copy number aberration profiles.
Samples of interest can be easily selected for visual comparison of multiple copy number profiles. An interactive searchable and zoomable view allows browsing specific genomic region of interest.
A hierarchical clustering of the samples is also provided to help investigating the relationships between samples and study tumor heterogeneity.
Ampli1™ and DEPArray OncoSeek Pipelines
The tailored analysis pipelines automate analysis of raw data produced from the sequencing of DNA libraries produced with Ampli1 OncoSeek Panel and DEPArray OncoSeek Panel and guarantees highly confident variant calling and focal copy number amplifications in selected target genes.
The list of putative somatic variants with basic annotation are ranked by relevance and the allelic frequencies of each variant and basic annotation are also provided.
The copy number amplifications section is available both in text format and as a barchart and displays the copy number amplifications in 19 target genes.
Bridge the gap between your raw NGS data and consolidated results
Two level of Reporting Available for the OncoSeek pipelines
Analytical Report with basic annotation of variant calling
Clinical interpretation report with advanced annotation
Clinical Interpretation Report
For OncoSeek pipelines, optional advanced annotation is available on demand.
Clinically relevant variants are classified by levels of known significance and layers of diagnostic, prognostic, therapeutic and biomarker evidence are integrated. The service also incorporates deep scientific and clinical analysis of each patient’s molecular data, to identify and prioritize the best clinical trial options.
The software is for research use only (RUO) and is not intended for use in a clinical setting and diagnostic procedures. Usage of the software signifies your acceptance of the Terms & Conditions for MSBiosuite Users.